Reconstitution chart: 5 mg vial
| BAC water added | Concentration | Draw for 200 mcg dose | Draw for 500 mcg dose |
|---|---|---|---|
| 1 mL | 5,000 mcg/mL | 4 units | 10 units |
| 1.5 mL | 3,333 mcg/mL | 6 units | 15 units |
| 2 mL | 2,500 mcg/mL | 8 units | 20 units |
| 2.5 mL | 2,000 mcg/mL | 10 units | 25 units |
Draws are U-100 insulin syringe units (100 units = 1 mL). Formula: dose in mcg ÷ (vial mcg ÷ water mL) × 100. The calculator above handles any other combination.
About Sermorelin
Sermorelin is the first 29 amino acids of human growth-hormone-releasing hormone, the fragment that carries essentially all of the hormone’s activity. It stands apart from most peptides on this site because it once held full FDA approval: it was marketed as Geref for pediatric growth hormone deficiency until 2008, when it was withdrawn for commercial reasons rather than safety findings. Today it is prescribed off-label through compounding pharmacies and longevity clinics.
Clinic protocols commonly run 100 to 500 mcg injected subcutaneously at night. The molecule itself clears in minutes, but the growth hormone pulse it triggers is the point, and that pulse pairs with the natural release that happens in early sleep. If a clinic prescribed yours, the vial usually arrives with reconstitution instructions; this calculator lets you verify their numbers instead of trusting them blind.
Compounded sermorelin vials come in odd sizes (9 mg is a common one) because pharmacies batch to prescription volumes rather than round numbers. The math handles any size: enter the actual labeled content. A 9 mg vial at 300 mcg nightly holds thirty doses, a clean month. Refrigerate after mixing and respect the beyond-use date your pharmacy printed.
Quick facts
- Status: formerly FDA approved (Geref, withdrawn 2008 for commercial reasons); now compounded off-label
- Half-life: minutes, but the triggered growth hormone pulse is the intended effect
- Clinic protocols commonly run 100 to 500 mcg nightly
- Vial sizes vary by pharmacy: 2, 5, 9, and 15 mg all circulate